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Predictive value and clinical significance of increased SSAT-1 activity in healthy adults

AIM: Spermidine/spermine N(1)-acetyltransferase (SSAT-1) regulates cell growth, proliferation and death. Amantadine is converted by SSAT-1 to acetylamantadine (AA). In our earlier studies, although SSAT-1 was activated in patients with cancer, a number of ostensibly healthy adult volunteers had high...

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Detalles Bibliográficos
Autores principales: Tappia, Paramjit S, Maksymiuk, Andrew W, Sitar, Daniel S, Akhtar, Parveen S, Khatun, Nazrina, Parveen, Rahnuma, Ahmed, Rashiduzzaman, Ahmed, Rashid B, Cheng, Brian, Huang, Gina, Bach, Horacio, Hiebert, Brett, Ramjiawan, Bram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695528/
https://www.ncbi.nlm.nih.gov/pubmed/31428447
http://dx.doi.org/10.2144/fsoa-2019-0023