Cargando…
GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme
Glycoprotein A repetition predominant (GARP), a specific surface molecule of activated regulatory T cells, has been demonstrated to significantly contribute to tolerance in humans by induction of peripheral Treg and regulatory M2-macrophages and by inhibition of (tumorantigen-specific) T effector ce...
Autores principales: | Zimmer, Niklas, Kim, Ella, Schupp, Jonathan, Sprang, Bettina, Leukel, Petra, Khafaji, Fatemeh, Ringel, Florian, Sommer, Clemens, Tuettenberg, Jochen, Tuettenberg, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695992/ https://www.ncbi.nlm.nih.gov/pubmed/31357555 http://dx.doi.org/10.3390/ijms20153676 |
Ejemplares similares
-
A key role of GARP in the immune suppressive tumor microenvironment
por: Hahn, Susanne A., et al.
Publicado: (2016) -
GARP as a Therapeutic Target for the Modulation of Regulatory T Cells in Cancer and Autoimmunity
por: Zimmer, Niklas, et al.
Publicado: (2022) -
ALDH1A3 Segregated Expression and Nucleus-Associated Proteasomal Degradation Are Common Traits of Glioblastoma Stem Cells
por: Fauß, Julian, et al.
Publicado: (2021) -
GARP Regulates the Immune Capacity of a Human Autologous Platelet Concentrate
por: Trzeciak, Emily R., et al.
Publicado: (2022) -
Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis
por: Zimmer, Niklas, et al.
Publicado: (2020)