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Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas

This paper presents a spatial analysis of the association between industrial benzene emissions and the 10-year incidence rates of cancers likely to be associated with benzene exposure (Lymphohematopoietic, lung and lip cancers) at the county level in Texas. The spatial distribution of incident cases...

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Autores principales: Mungi, Chinmay, Lai, Dejian, Du, Xianglin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696035/
https://www.ncbi.nlm.nih.gov/pubmed/31344779
http://dx.doi.org/10.3390/ijerph16152627
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author Mungi, Chinmay
Lai, Dejian
Du, Xianglin L.
author_facet Mungi, Chinmay
Lai, Dejian
Du, Xianglin L.
author_sort Mungi, Chinmay
collection PubMed
description This paper presents a spatial analysis of the association between industrial benzene emissions and the 10-year incidence rates of cancers likely to be associated with benzene exposure (Lymphohematopoietic, lung and lip cancers) at the county level in Texas. The spatial distribution of incident cases of the above cancers between 2004 and 2013 was assessed at the county level and found to have positive spatial auto-correlation. Subsequently, point pattern analysis was performed on industrial emissions of benzene reported to the Toxic Release Inventory (TRI), revealing a non-random spatial pattern. Universal kriging was performed using the industrial emissions data to derive estimates of ambient benzene levels at the county level. An ordinary linear regression model was fitted using the incidence rates as the outcome and the estimated benzene level along with chosen covariates and the residuals were assessed for lingering spatial auto-correlation. As the residuals showed that spatial auto-correlation persists, a spatial conditional auto-regression (CAR) model was fitted instead. In the spatial CAR linear regression model, estimated levels of ambient benzene were not found to be significantly associated with the 10-year incidence rates of lymphohematopoietic, lung and lip cancers at the county level.
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spelling pubmed-66960352019-09-05 Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas Mungi, Chinmay Lai, Dejian Du, Xianglin L. Int J Environ Res Public Health Article This paper presents a spatial analysis of the association between industrial benzene emissions and the 10-year incidence rates of cancers likely to be associated with benzene exposure (Lymphohematopoietic, lung and lip cancers) at the county level in Texas. The spatial distribution of incident cases of the above cancers between 2004 and 2013 was assessed at the county level and found to have positive spatial auto-correlation. Subsequently, point pattern analysis was performed on industrial emissions of benzene reported to the Toxic Release Inventory (TRI), revealing a non-random spatial pattern. Universal kriging was performed using the industrial emissions data to derive estimates of ambient benzene levels at the county level. An ordinary linear regression model was fitted using the incidence rates as the outcome and the estimated benzene level along with chosen covariates and the residuals were assessed for lingering spatial auto-correlation. As the residuals showed that spatial auto-correlation persists, a spatial conditional auto-regression (CAR) model was fitted instead. In the spatial CAR linear regression model, estimated levels of ambient benzene were not found to be significantly associated with the 10-year incidence rates of lymphohematopoietic, lung and lip cancers at the county level. MDPI 2019-07-24 2019-08 /pmc/articles/PMC6696035/ /pubmed/31344779 http://dx.doi.org/10.3390/ijerph16152627 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mungi, Chinmay
Lai, Dejian
Du, Xianglin L.
Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas
title Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas
title_full Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas
title_fullStr Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas
title_full_unstemmed Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas
title_short Spatial Analysis of Industrial Benzene Emissions and Cancer Incidence Rates in Texas
title_sort spatial analysis of industrial benzene emissions and cancer incidence rates in texas
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696035/
https://www.ncbi.nlm.nih.gov/pubmed/31344779
http://dx.doi.org/10.3390/ijerph16152627
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