Cargando…

Methylation of the RELA Gene is Associated with Expression of NF-κB1 in Response to TNF-α in Breast Cancer

The nuclear factor (NF)-κB family of transcriptional factors plays a critical role in inflammation, immunoregulation, cell differentiation, and tumorigenesis. This study aims to investigate the role of methylation of genes encoding for the NF-κB family in breast cancer. We analyze the DNA methylatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeong, Young Ju, Oh, Hoon Kyu, Choi, Hye Ryeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696039/ https://www.ncbi.nlm.nih.gov/pubmed/31382678 http://dx.doi.org/10.3390/molecules24152834

Ejemplares similares

Celecoxib Suppresses NF-κB p65 (RelA) and TNFα Expression Signaling in Glioblastoma
por: Ahsan, Hina, et al.
Publicado: (2023)

Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA
por: Kour, Smit, et al.
Publicado: (2021)

An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisions
por: Oliver Metzig, Marie, et al.
Publicado: (2020)

Methylation of the NT5E Gene Is Associated with Poor Prognostic Factors in Breast Cancer
por: Jeong, Young Ju, et al.
Publicado: (2020)

NF-κB Repression by PIAS3 Mediated RelA SUMOylation
por: Liu, Yuangang, et al.
Publicado: (2012)

IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer
por: Tsui, Rachel, et al.
Publicado: (2015)

The Clinical Significance of PR, ER, NF-κB, and TNF-α in Breast Cancer
por: Zhou, Xian-Long, et al.
Publicado: (2014)

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination
por: Li, Haiying, et al.
Publicado: (2011)

SETD6 lysine methylation of RelA couples GLP activity at chromatin to tonic repression of NF-κB signaling
por: Levy, Dan, et al.
Publicado: (2010)

Single TNFα trimers mediating NF-κB activation: stochastic robustness of NF-κB signaling
por: Lipniacki, Tomasz, et al.
Publicado: (2007)

Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs
por: Alcamo, Elizabeth, et al.
Publicado: (2002)

PTPIP51—A New RelA-tionship with the NFκB Signaling Pathway
por: Brobeil, Alexander, et al.
Publicado: (2015)

The NF-κB RelA Transcription Factor Is Critical for Regulatory T Cell Activation and Stability
por: Ronin, Emilie, et al.
Publicado: (2019)

NFκB (RelA) mediates transactivation of hnRNPD in oral cancer cells
por: Kumar, Vikas, et al.
Publicado: (2022)

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA
por: Oyegunwa, Akinbolade O, et al.
Publicado: (2010)

Cyclophilin A (CypA) Interacts with NF-κB Subunit, p65/RelA, and Contributes to NF-κB Activation Signaling
por: Sun, Shan, et al.
Publicado: (2014)

RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma
por: Zhang, Mingzhi, et al.
Publicado: (2016)

Distinct B subunits of PP2A regulate the NF‐κB signalling pathway through dephosphorylation of IKKβ, IκBα and RelA
por: Tsuchiya, Yoshihiro, et al.
Publicado: (2017)

Thr(435) phosphorylation regulates RelA (p65) NF-κB subunit transactivation
por: O'Shea, John M., et al.
Publicado: (2010)

C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma
por: Parker, Matthew, et al.
Publicado: (2014)

NF-κB/RelA-PKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells
por: Han, Dongfeng, et al.
Publicado: (2015)

Differential expression of NF-κB heterodimer RelA/p50 in human urothelial carcinoma
por: Durairajan, Sankari, et al.
Publicado: (2018)

Temporal modulation of the NF-κB RelA network in response to different types of DNA damage
por: Campbell, Amy E., et al.
Publicado: (2021)

NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer
por: Koerner, Lioba, et al.
Publicado: (2023)

NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB
por: Kabacaoglu, Derya, et al.
Publicado: (2019)

Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth
por: Kanzaki, Hirotaka, et al.
Publicado: (2021)

The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury
por: Lanzillotta, A, et al.
Publicado: (2010)

The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury
Publicado: (2010)

NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
por: Geismann, Claudia, et al.
Publicado: (2023)

TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
por: Wu, Y, et al.
Publicado: (2010)

Extracellular ATP Activates Transcription Factor NF-κB through the P2Z Purinoreceptor by Selectively Targeting NF-κB p65 (RelA)
por: Ferrari, Davide, et al.
Publicado: (1997)

TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation
por: Kim, Eunju, et al.
Publicado: (2023)

Similar NF-κB Gene Signatures in TNF-α Treated Human Endothelial Cells and Breast Tumor Biopsies
por: Perrot-Applanat, Martine, et al.
Publicado: (2011)

Mechanism of Probiotic VSL#3 Inhibiting NF-κB and TNF-α on Colitis through TLR4-NF-κB Signal Pathway
por: WANG, Hui, et al.
Publicado: (2019)

Enterovirus 71 2C Protein Inhibits NF-κB Activation by Binding to RelA(p65)
por: Du, Haiwei, et al.
Publicado: (2015)

Involvement of Egr-1/RelA Synergy in Distinguishing T Cell Activation from Tumor Necrosis Factor-α–induced NF-κB1 Transcription
por: Cogswell, Patricia C., et al.
Publicado: (1997)

Optineurin Is Required for CYLD-Dependent Inhibition of TNFα-Induced NF-κB Activation
por: Nagabhushana, Ananthamurthy, et al.
Publicado: (2011)

Spontaneous NF-κB Activation by Autocrine TNFα Signaling: A Computational Analysis
por: Pękalski, Jakub, et al.
Publicado: (2013)

TNF-α and RANKL promote osteoclastogenesis by upregulating RANK via the NF-κB pathway
por: Luo, Gang, et al.
Publicado: (2018)

Expression and Significance of TNF-α and NF-κB/p65 in Cutaneous Lichen Planus
por: Chen, Jun Fang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0h1ibh4lq22pj28pui1nrpdgtk