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Pharmacophoric Site Identification and Inhibitor Design for Autotaxin

Autotaxin (ATX) is a potential drug target that is associated with inflammatory diseases and various cancers. In our previous studies, we have designed several inhibitors targeting ATX using computational and experimental approaches. Here, we have analyzed topological water networks (TWNs) in the bi...

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Detalles Bibliográficos
Autores principales:	Lee, Myeong Hwi, Lee, Dae-Yon, Balupuri, Anand, Jeong, Jong-Woo, Kang, Nam Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696049/ https://www.ncbi.nlm.nih.gov/pubmed/31374894 http://dx.doi.org/10.3390/molecules24152808

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