Cargando…

Targeting Long Chain Acyl-CoA Synthetases for Cancer Therapy

The deregulation of cancer cell metabolic networks is now recognized as one of the hallmarks of cancer. Abnormal lipid synthesis and extracellular lipid uptake are advantageous modifications fueling the needs of uncontrolled cancer cell proliferation. Fatty acids are placed at the crossroads of anab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rossi Sebastiano, Matteo, Konstantinidou, Georgia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696099/ https://www.ncbi.nlm.nih.gov/pubmed/31344914 http://dx.doi.org/10.3390/ijms20153624

Ejemplares similares

Long-Chain Acyl-CoA Synthetase is Associated with the Growth of Malassezia spp.
por: Tenagy,, et al.
Publicado: (2019)

Long-chain bases of sphingolipids are transported into cells via the acyl-CoA synthetases
por: Narita, Tomomi, et al.
Publicado: (2016)

Very Long-Chain Acyl-CoA Synthetase 3: Overexpression and Growth Dependence in Lung Cancer
por: Pei, Zhengtong, et al.
Publicado: (2013)

Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity
por: Ruiz, Mario, et al.
Publicado: (2019)

Diversity and history of the long-chain acyl-CoA synthetase (Acsl) gene family in vertebrates
por: Lopes-Marques, Mónica, et al.
Publicado: (2013)

Functional Role of Long-Chain Acyl-CoA Synthetases in Plant Development and Stress Responses
por: Zhao, Huayan, et al.
Publicado: (2021)

Long-chain acyl-CoA synthetase 2 is involved in seed oil production in Brassica napus
por: Ding, Li-Na, et al.
Publicado: (2020)

Giardia fatty acyl-CoA synthetases as potential drug targets
por: Guo, Fengguang, et al.
Publicado: (2015)

The effect of acyl-CoA synthetase long-chain family member 5 on triglyceride synthesis in bovine preadipocytes
por: Yu, Xiang, et al.
Publicado: (2019)

A Peroxisomal Long-Chain Acyl-CoA Synthetase from Glycine max Involved in Lipid Degradation
por: Yu, Lili, et al.
Publicado: (2014)

Chlamydia trachomatis growth and development requires the activity of host Long-chain Acyl-CoA Synthetases (ACSLs)
por: Recuero-Checa, Maria A., et al.
Publicado: (2016)

Long-Chain Acyl-CoA Synthetases Promote Poplar Resistance to Abiotic Stress by Regulating Long-Chain Fatty Acid Biosynthesis
por: Wei, Hui, et al.
Publicado: (2022)

Fatty acid metabolism and acyl-CoA synthetases in the liver-gut axis
por: Ma, Yunxia, et al.
Publicado: (2021)

Long Chain Fatty Acyl-CoA Synthetase 4 Is a Biomarker for and Mediator of Hormone Resistance in Human Breast Cancer
por: Wu, Xinyu, et al.
Publicado: (2013)

Role of Sinorhizobium meliloti and Escherichia coli Long-Chain Acyl-CoA Synthetase FadD in Long-Term Survival
por: Pech-Canul, Ángel de la Cruz, et al.
Publicado: (2020)

Modulation of long-chain Acyl-CoA synthetase on the development, lipid deposit and cryosurvival of in vitro produced bovine embryos
por: Valente, Roniele Santana, et al.
Publicado: (2019)

Long-Chain acyl-CoA Synthetase LACS2 Contributes to Submergence Tolerance by Modulating Cuticle Permeability in Arabidopsis
por: Xie, Li-Juan, et al.
Publicado: (2020)

Cardiac Hypertrophy in Mice with Long-Chain Acyl-CoA Dehydrogenase (LCAD) or Very Long-Chain Acyl-CoA Dehydrogenase (VLCAD) Deficiency
por: Cox, Keith B., et al.
Publicado: (2009)

Regulated Acyl-CoA Synthetase Short-Chain Family Member 2 Accumulation during Spermatogenesis
por: Goudarzi, Afsaneh, et al.
Publicado: (2020)

The Roles of Coenzyme A Binding Pocket Residues in Short and Medium Chain Acyl-CoA Synthetases
por: Meng, Yu, et al.
Publicado: (2023)

A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus
por: Whaley, Sarah G., et al.
Publicado: (2023)

Targeting of Acyl-CoA synthetase 5 decreases jejunal fatty acid activation with no effect on dietary long-chain fatty acid absorption
por: Meller, Nahum, et al.
Publicado: (2013)

Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains
por: Soupene, Eric, et al.
Publicado: (2006)

Characterization of long-chain acyl-CoA synthetases which stimulate secretion of fatty acids in green algae Chlamydomonas reinhardtii
por: Jia, Bin, et al.
Publicado: (2016)

Effects of Long-Chain Fatty Acyl-CoA Synthetase 1 on Diglyceride Synthesis and Arachidonic Acid Metabolism in Sheep Adipocytes
por: Cao, Yang, et al.
Publicado: (2020)

Functional Analysis of Rice Long-Chain Acyl-CoA Synthetase 9 (OsLACS9) in the Chloroplast Envelope Membrane
por: Kitajima-Koga, Aya, et al.
Publicado: (2020)

Enhancement of E. coli acyl-CoA synthetase FadD activity on medium chain fatty acids
por: Ford, Tyler J., et al.
Publicado: (2015)

Acyl-CoA Synthetase 5 Promotes the Growth and Invasion of Colorectal Cancer Cells
por: Ding, Shihua, et al.
Publicado: (2017)

Genetic Alteration, Prognostic and Immunological Role of Acyl-CoA Synthetase Long-Chain Family Member 4 in a Pan-Cancer Analysis
por: Yu, Yongsheng, et al.
Publicado: (2022)

Long chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation
por: Ma, Yongjie, et al.
Publicado: (2021)

Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis
por: Chen, Junmin, et al.
Publicado: (2021)

Long chain acyl CoA synthetase 4 catalyzes the first step in peroxisomal indole-3-butyric acid to IAA conversion
por: Jawahir, Vanessica, et al.
Publicado: (2020)

Cinnamon extract improves abnormalities in glucose tolerance by decreasing Acyl-CoA synthetase long-chain family 1 expression in adipocytes
por: Nishikai-Shen, Tsubame, et al.
Publicado: (2022)

Genome-Wide Identification, Characterization, and Expression Analysis of Long-Chain Acyl-CoA Synthetases in Carya illinoinensis under Different Treatments
por: Ma, Wenjuan, et al.
Publicado: (2023)

Intracellular Long-Chain Acyl CoAs Activate TRPV1 Channels
por: Yu, Yi, et al.
Publicado: (2014)

LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1
por: Al-Rashed, Fatema, et al.
Publicado: (2020)

Genome-Wide Identification and Expression Profiling Analysis of the Long-Chain Acyl-CoA Synthetases Reveal Their Potential Roles in Wheat Male Fertility
por: Liu, Yongjie, et al.
Publicado: (2022)

Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains
por: Kassan, Adam, et al.
Publicado: (2013)

An Acyl-CoA Synthetase in Mycobacterium tuberculosis Involved in Triacylglycerol Accumulation during Dormancy
por: Daniel, Jaiyanth, et al.
Publicado: (2014)

Acetate Revisited: A Key Biomolecule at the Nexus of Metabolism, Epigenetics and Oncogenesis—Part 1: Acetyl-CoA, Acetogenesis and Acyl-CoA Short-Chain Synthetases
por: Moffett, John R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4nj615o32r7e8hkrjaib3av4q2