Cargando…

Very Low Resource Digital Implementation of Bioimpedance Analysis †

Bioimpedance spectroscopy consists of measuring the complex impedance of biological tissues over a large frequency domain. This method is particularly convenient for physiological studies or health monitoring systems. For a wide range of applications, devices need to be portable, wearable or even im...

Descripción completa

Detalles Bibliográficos
Autores principales: Soulier, Fabien, Lamlih, Achraf, Kerzérho, Vincent, Bernard, Serge, Rouyer, Tristan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696154/
https://www.ncbi.nlm.nih.gov/pubmed/31374915
http://dx.doi.org/10.3390/s19153381
_version_ 1783444203809800192
author Soulier, Fabien
Lamlih, Achraf
Kerzérho, Vincent
Bernard, Serge
Rouyer, Tristan
author_facet Soulier, Fabien
Lamlih, Achraf
Kerzérho, Vincent
Bernard, Serge
Rouyer, Tristan
author_sort Soulier, Fabien
collection PubMed
description Bioimpedance spectroscopy consists of measuring the complex impedance of biological tissues over a large frequency domain. This method is particularly convenient for physiological studies or health monitoring systems. For a wide range of applications, devices need to be portable, wearable or even implantable. Next generation of bioimpedance sensing systems thus require to be implemented with power and resource savings in mind. Impedance measurement methods are divided into two main categories. Some are based on “single-tone” signals while the others use “multi-tone” signals. The firsts benefit from a very simple analysis that may consist of synchronous demodulation. However, due to necessary frequency sweep, the total measurement may take a long time. On the other hand, generating a multi-frequency signal allows the seconds to cover the whole frequency range simultaneously. This is at the cost of a more complex analysis algorithm. This makes both approaches hardly suitable for embedded applications. In this paper, we propose an intermediate approach that combines the speed of multi-tone systems with a low-resource analysis algorithm. This results in a minimal implementation using only adders and synchronous adc. For optimal performances, this small footprint digital processing can be synthesized and embedded on a mixed-mode integrated circuit together with the analog front-end. Moreover, the proposed implementation is easily scalable to fit an arbitrary frequency range. We also show that the resulting impact on noise sensitivity can be mitigated.
format Online
Article
Text
id pubmed-6696154
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-66961542019-09-05 Very Low Resource Digital Implementation of Bioimpedance Analysis † Soulier, Fabien Lamlih, Achraf Kerzérho, Vincent Bernard, Serge Rouyer, Tristan Sensors (Basel) Article Bioimpedance spectroscopy consists of measuring the complex impedance of biological tissues over a large frequency domain. This method is particularly convenient for physiological studies or health monitoring systems. For a wide range of applications, devices need to be portable, wearable or even implantable. Next generation of bioimpedance sensing systems thus require to be implemented with power and resource savings in mind. Impedance measurement methods are divided into two main categories. Some are based on “single-tone” signals while the others use “multi-tone” signals. The firsts benefit from a very simple analysis that may consist of synchronous demodulation. However, due to necessary frequency sweep, the total measurement may take a long time. On the other hand, generating a multi-frequency signal allows the seconds to cover the whole frequency range simultaneously. This is at the cost of a more complex analysis algorithm. This makes both approaches hardly suitable for embedded applications. In this paper, we propose an intermediate approach that combines the speed of multi-tone systems with a low-resource analysis algorithm. This results in a minimal implementation using only adders and synchronous adc. For optimal performances, this small footprint digital processing can be synthesized and embedded on a mixed-mode integrated circuit together with the analog front-end. Moreover, the proposed implementation is easily scalable to fit an arbitrary frequency range. We also show that the resulting impact on noise sensitivity can be mitigated. MDPI 2019-08-01 /pmc/articles/PMC6696154/ /pubmed/31374915 http://dx.doi.org/10.3390/s19153381 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Soulier, Fabien
Lamlih, Achraf
Kerzérho, Vincent
Bernard, Serge
Rouyer, Tristan
Very Low Resource Digital Implementation of Bioimpedance Analysis †
title Very Low Resource Digital Implementation of Bioimpedance Analysis †
title_full Very Low Resource Digital Implementation of Bioimpedance Analysis †
title_fullStr Very Low Resource Digital Implementation of Bioimpedance Analysis †
title_full_unstemmed Very Low Resource Digital Implementation of Bioimpedance Analysis †
title_short Very Low Resource Digital Implementation of Bioimpedance Analysis †
title_sort very low resource digital implementation of bioimpedance analysis †
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696154/
https://www.ncbi.nlm.nih.gov/pubmed/31374915
http://dx.doi.org/10.3390/s19153381
work_keys_str_mv AT soulierfabien verylowresourcedigitalimplementationofbioimpedanceanalysis
AT lamlihachraf verylowresourcedigitalimplementationofbioimpedanceanalysis
AT kerzerhovincent verylowresourcedigitalimplementationofbioimpedanceanalysis
AT bernardserge verylowresourcedigitalimplementationofbioimpedanceanalysis
AT rouyertristan verylowresourcedigitalimplementationofbioimpedanceanalysis