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Proteasome Activation to Combat Proteotoxicity

Loss of proteome fidelity leads to the accumulation of non-native protein aggregates and oxidatively damaged species: hallmarks of an aged cell. These misfolded and aggregated species are often found, and suggested to be the culpable party, in numerous neurodegenerative diseases including Huntington...

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Detalles Bibliográficos
Autores principales: Jones, Corey L., Tepe, Jetze J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696185/
https://www.ncbi.nlm.nih.gov/pubmed/31387243
http://dx.doi.org/10.3390/molecules24152841