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Compromised Barrier Function in Human Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells from Type 2 Diabetic Patients

In diabetic patients, high blood glucose induces alterations in retinal function and can lead to visual impairment due to diabetic retinopathy. In immortalized retinal pigment epithelial (RPE) cultures, high glucose concentrations are shown to lead to impairment in epithelial barrier properties. For...

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Detalles Bibliográficos
Autores principales:	Kiamehr, Mostafa, Klettner, Alexa, Richert, Elisabeth, Koskela, Ali, Koistinen, Arto, Skottman, Heli, Kaarniranta, Kai, Aalto-Setälä, Katriina, Juuti-Uusitalo, Kati
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696227/ https://www.ncbi.nlm.nih.gov/pubmed/31375001 http://dx.doi.org/10.3390/ijms20153773

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