Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[e]imidazo[2,1-c][1,2,4]triazines as Phosphodiesterase 2A Inhibitors

Phosphodiesterase 2A (PDE2A) is highly expressed in distinct areas of the brain, which are known to be related to neuropsychiatric diseases. The development of suitable PDE2A tracers for Positron Emission Tomography (PET) would permit the in vivo imaging of the PDE2A and evaluation of disease-mediat...

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Detalles Bibliográficos
Autores principales: Ritawidya, Rien, Ludwig, Friedrich-Alexander, Briel, Detlef, Brust, Peter, Scheunemann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696243/
https://www.ncbi.nlm.nih.gov/pubmed/31370274
http://dx.doi.org/10.3390/molecules24152791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696243/
https://www.ncbi.nlm.nih.gov/pubmed/31370274
http://dx.doi.org/10.3390/molecules24152791

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