Cargando…

Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells

Licochalcone A (LCA) is a chalcone that is predominantly found in the root of Glycyrrhiza species, which is widely used as an herbal medicine. Although previous studies have reported that LCA has a wide range of pharmacological effects, evidence for the underlying molecular mechanism of its anti-can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Su Hyun, Cha, Hee-Jae, Hwang-Bo, Hyun, Kim, Min Yeong, Kim, So Young, Ji, Seon Yeong, Cheong, JaeHun, Park, Cheol, Lee, Hyesook, Kim, Gi-Young, Moon, Sung-Kwon, Yun, Seok Joong, Chang, Young-Chae, Kim, Wun-Jae, Choi, Yung Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696302/ https://www.ncbi.nlm.nih.gov/pubmed/31387245 http://dx.doi.org/10.3390/ijms20153820

Ejemplares similares

Isorhamnetin Induces Cell Cycle Arrest and Apoptosis Via Reactive Oxygen Species-Mediated AMP-Activated Protein Kinase Signaling Pathway Activation in Human Bladder Cancer Cells
por: Park, Cheol, et al.
Publicado: (2019)

Betulinic Acid Restricts Human Bladder Cancer Cell Proliferation In Vitro by Inducing Caspase-Dependent Cell Death and Cell Cycle Arrest, and Decreasing Metastatic Potential
por: Kim, So Young, et al.
Publicado: (2021)

Anti-Inflammatory Effect of Auranofin on Palmitic Acid and LPS-Induced Inflammatory Response by Modulating TLR4 and NOX4-Mediated NF-κB Signaling Pathway in RAW264.7 Macrophages
por: Hwangbo, Hyun, et al.
Publicado: (2021)

Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway
por: Kim, So Young, et al.
Publicado: (2020)

ROS-Mediated Anti-Tumor Effect of Coptidis Rhizoma against Human Hepatocellular Carcinoma Hep3B Cells and Xenografts
por: Kim, So Young, et al.
Publicado: (2021)

Induction of G2/M Cell Cycle Arrest and Apoptosis by Genistein in Human Bladder Cancer T24 Cells through Inhibition of the ROS-Dependent PI3k/Akt Signal Transduction Pathway
por: Park, Cheol, et al.
Publicado: (2019)

Phloroglucinol Attenuates DNA Damage and Apoptosis Induced by Oxidative Stress in Human Retinal Pigment Epithelium ARPE-19 Cells by Blocking the Production of Mitochondrial ROS
por: Park, Cheol, et al.
Publicado: (2022)

Spermidine Attenuates Oxidative Stress-Induced Apoptosis via Blocking Ca(2+) Overload in Retinal Pigment Epithelial Cells Independently of ROS
por: Kim, Da Hye, et al.
Publicado: (2021)

Auranofin Attenuates Non-Alcoholic Fatty Liver Disease by Suppressing Lipid Accumulation and NLRP3 Inflammasome-Mediated Hepatic Inflammation In Vivo and In Vitro
por: Hwangbo, Hyun, et al.
Publicado: (2020)

Ethanol Extract of Hizikia fusiforme Induces Apoptosis in B16F10 Mouse Melanoma Cells through ROS-Dependent Inhibition of the PI3K/Akt Signaling Pathway
por: Park, Cheol, et al.
Publicado: (2020)

Induction of apoptotic cell death in human bladder cancer cells by ethanol extract of Zanthoxylum schinifolium leaf, through ROS-dependent inactivation of the PI3K/Akt signaling pathway
por: Park, Cheol, et al.
Publicado: (2022)

Induction of Apoptosis by Isoalantolactone in Human Hepatocellular Carcinoma Hep3B Cells through Activation of the ROS-Dependent JNK Signaling Pathway
por: Kim, Min Yeong, et al.
Publicado: (2021)

Schisandrae Fructus ethanol extract attenuates particulate matter 2.5-induced inflammatory and oxidative responses by blocking the activation of the ROS-dependent NF-κB signaling pathway
por: Lee, Hyesook, et al.
Publicado: (2021)

Citrus unshiu peel suppress the metastatic potential of murine melanoma B16F10 cells in vitro and in vivo
por: Choi, Eun Ok, et al.
Publicado: (2019)

Honokiol ameliorates oxidative stress-induced DNA damage and apoptosis of c2c12 myoblasts by ROS generation and mitochondrial pathway
por: Park, Cheol, et al.
Publicado: (2019)

Sex Difference on Neurological Outcomes and Post-Cardiac Arrest Care in Out-of-Hospital Cardiac Arrest Patients Treated with Targeted Temperature Management: Post-Hoc Study of a Prospective, Multicenter, Observational Cohort Study
por: Park, Seon Yeong, et al.
Publicado: (2023)

Licochalcone H Induces Cell Cycle Arrest and Apoptosis in Human Skin Cancer Cells by Modulating JAK2/STAT3 Signaling
por: Park, Kyung-Ho, et al.
Publicado: (2022)

Suppression of Lipopolysaccharide-Induced Inflammatory and Oxidative Response by 5-Aminolevulinic Acid in RAW 264.7 Macrophages and Zebrafish Larvae
por: Ji, Seon Yeong, et al.
Publicado: (2021)

The immunostimulatory effect of indole-6-carboxaldehyde isolated from Sargassum thunbergii (Mertens) Kuntze in RAW 264.7 macrophages
por: Park, Cheol, et al.
Publicado: (2020)

A Novel Peptide Oligomer of Bacitracin Induces M1 Macrophage Polarization by Facilitating Ca(2+) Influx
por: Ji, Seon Yeong, et al.
Publicado: (2020)

The Protective Effect of Oral Application of Corni Fructus on the Disorders of the Cornea, Conjunctiva, Lacrimal Gland and Retina by Topical Particulate Matter 2.5
por: Lee, Hyesook, et al.
Publicado: (2021)

Associations of Apoptotic and Anti-Apoptotic Factors with Beef Quality, Histochemical Characteristics, and Palatability of Hanwoo Longissimus thoracis Muscle
por: Lee, Boin, et al.
Publicado: (2022)

Hepatic STAMP2 decreases hepatitis B virus X protein-associated metabolic deregulation
por: Kim, Hye Young, et al.
Publicado: (2012)

Licochalcone B Induces ROS-Dependent Apoptosis in Oxaliplatin-Resistant Colorectal Cancer Cells via p38/JNK MAPK Signaling
por: Kwak, Ah-Won, et al.
Publicado: (2023)

Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET
por: Oh, Ha-Na, et al.
Publicado: (2020)

Glutathione Induced Immune-Stimulatory Activity by Promoting M1-Like Macrophages Polarization via Potential ROS Scavenging Capacity
por: Kwon, Da Hye, et al.
Publicado: (2019)

Anti-Proliferative and Apoptotic Activities of Müllerian Inhibiting Substance Combined with Calcitriol in Ovarian Cancer Cell Lines
por: Jung, Yeon Soo, et al.
Publicado: (2016)

The Protective Effect of Topical Spermidine on Dry Eye Disease with Retinal Damage Induced by Diesel Particulate Matter2.5
por: Lee, Hyesook, et al.
Publicado: (2021)

Inhibiting Invasion into Human Bladder Carcinoma 5637 Cells with Diallyl Trisulfide by Inhibiting Matrix Metalloproteinase Activities and Tightening Tight Junctions
por: Shin, Dong Yeok, et al.
Publicado: (2013)

Fermented Sea Tangle (Laminaria japonica Aresch) Suppresses RANKL-Induced Osteoclastogenesis by Scavenging ROS in RAW 264.7 Cells
por: Jeong, Jin-Woo, et al.
Publicado: (2019)

Induction of Apoptosis by Fucoidan in Human Leukemia U937 Cells through Activation of p38 MAPK and Modulation of Bcl-2 Family
por: Park, Hyun Soo, et al.
Publicado: (2013)

Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review
por: Kim, Gi-Young, et al.
Publicado: (2011)

Correction: Kim, G.-Y. et al. Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent-A Review. Mar. Drugs 2011, 9, 2176-2187
por: Kim, Gi-Young, et al.
Publicado: (2013)

The anti-cancer effect of betulinic acid in u937 human leukemia cells is mediated through ROS-dependent cell cycle arrest and apoptosis
por: Park, Cheol, et al.
Publicado: (2021)

Phloroglucinol Inhibits Oxidative-Stress-Induced Cytotoxicity in C2C12 Murine Myoblasts through Nrf-2-Mediated Activation of HO-1
por: Park, Cheol, et al.
Publicado: (2023)

STAMPing into Mitochondria
por: Yoo, Seong Keun, et al.
Publicado: (2014)

Fisetin Protects C2C12 Mouse Myoblasts from Oxidative Stress-Induced Cytotoxicity through Regulation of the Nrf2/HO-1 Signaling
por: Park, Cheol, et al.
Publicado: (2023)

Effect of fermented oyster extract on growth promotion in Sprague–Dawley rats
por: Lee, Hyesook, et al.
Publicado: (2020)

Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway
por: Hwangbo, Hyun, et al.
Publicado: (2020)

Protective Effect of Gamma Aminobutyric Acid against Aggravation of Renal Injury Caused by High Salt Intake in Cisplatin-Induced Nephrotoxicity
por: Lee, Hyesook, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_30tquok9ir2vpti3s570id4cbe