Solid-State Characterization of Different Crystalline Forms of Sitagliptin

Sitagliptin is an inhibitor of the enzyme dipeptidyl peptidase-4, used for the treatment of type 2 diabetes mellitus. The crystal structure of active pharmaceutical solids determines their physical and chemical properties. The polymorphism, solvates and hydrates can influence the free energy, thermo...

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Detalles Bibliográficos
Autores principales: Stofella, Nayana C. F., Veiga, Andressa, Oliveira, Laiane J., Montin, Elisa F., Andreazza, Itamar F., Carvalho Filho, Marco A. S., Bernardi, Larissa S., Oliveira, Paulo R., Murakami, Fábio S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696402/
https://www.ncbi.nlm.nih.gov/pubmed/31344887
http://dx.doi.org/10.3390/ma12152351

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