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Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage

This study explores the effect of physical aging and/or crystallization on the supersaturation potential and crystallization kinetics of amorphous active pharmaceutical ingredients (APIs). Spray-dried, fully amorphous indapamide, metolazone, glibenclamide, hydrocortisone, hydrochlorothiazide, ketoco...

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Detalles Bibliográficos
Autores principales: Edueng, Khadijah, Mahlin, Denny, Gråsjö, Johan, Nylander, Olivia, Thakrani, Manish, Bergström, Christel A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696415/
https://www.ncbi.nlm.nih.gov/pubmed/31357587
http://dx.doi.org/10.3390/molecules24152731