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Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage
This study explores the effect of physical aging and/or crystallization on the supersaturation potential and crystallization kinetics of amorphous active pharmaceutical ingredients (APIs). Spray-dried, fully amorphous indapamide, metolazone, glibenclamide, hydrocortisone, hydrochlorothiazide, ketoco...
Autores principales: | Edueng, Khadijah, Mahlin, Denny, Gråsjö, Johan, Nylander, Olivia, Thakrani, Manish, Bergström, Christel A.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696415/ https://www.ncbi.nlm.nih.gov/pubmed/31357587 http://dx.doi.org/10.3390/molecules24152731 |
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