Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction

A concise and efficient approach to synthesizing coumarin-fused pyrazolo[3,4-b]pyridine via silica sulfuric acid (SSA) catalyzed three-component domino reaction under microwave irradiation has been demonstrated. Participation of various alcohols in construction of coumarin derivatives has been descr...

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Detalles Bibliográficos
Autores principales: Lin, Wei, Zhuang, Cangwei, Hu, Xiuxiu, Zhang, Juanjuan, Wang, Juxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696490/
https://www.ncbi.nlm.nih.gov/pubmed/31382711
http://dx.doi.org/10.3390/molecules24152835
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author Lin, Wei
Zhuang, Cangwei
Hu, Xiuxiu
Zhang, Juanjuan
Wang, Juxian
author_facet Lin, Wei
Zhuang, Cangwei
Hu, Xiuxiu
Zhang, Juanjuan
Wang, Juxian
author_sort Lin, Wei
collection PubMed
description A concise and efficient approach to synthesizing coumarin-fused pyrazolo[3,4-b]pyridine via silica sulfuric acid (SSA) catalyzed three-component domino reaction under microwave irradiation has been demonstrated. Participation of various alcohols in construction of coumarin derivatives has been described for the first time. Short reaction time, high yields, one-pot procedure, usage of eco-friendly catalyst, and solvent are the key features of this method.
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spelling pubmed-66964902019-09-05 Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction Lin, Wei Zhuang, Cangwei Hu, Xiuxiu Zhang, Juanjuan Wang, Juxian Molecules Article A concise and efficient approach to synthesizing coumarin-fused pyrazolo[3,4-b]pyridine via silica sulfuric acid (SSA) catalyzed three-component domino reaction under microwave irradiation has been demonstrated. Participation of various alcohols in construction of coumarin derivatives has been described for the first time. Short reaction time, high yields, one-pot procedure, usage of eco-friendly catalyst, and solvent are the key features of this method. MDPI 2019-08-04 /pmc/articles/PMC6696490/ /pubmed/31382711 http://dx.doi.org/10.3390/molecules24152835 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Wei
Zhuang, Cangwei
Hu, Xiuxiu
Zhang, Juanjuan
Wang, Juxian
Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction
title Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction
title_full Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction
title_fullStr Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction
title_full_unstemmed Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction
title_short Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction
title_sort alcohol participates in the synthesis of functionalized coumarin-fused pyrazolo[3,4-b]pyridine from a one-pot three-component reaction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696490/
https://www.ncbi.nlm.nih.gov/pubmed/31382711
http://dx.doi.org/10.3390/molecules24152835
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AT zhangjuanjuan alcoholparticipatesinthesynthesisoffunctionalizedcoumarinfusedpyrazolo34bpyridinefromaonepotthreecomponentreaction
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