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Antimicrobial Stewardship in the Neonatal Intensive Care Unit: An Update

Neonates represent a vulnerable population for infections and neonatal sepsis is a major cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most commonly pre-scribed drugs in the Neonatal Intensive Care Unit Setting but unfortunately are quite often used inap-propriately w...

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Detalles Bibliográficos
Autores principales: Gkentzi, Despoina, Dimitriou, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696821/
https://www.ncbi.nlm.nih.gov/pubmed/30657041
http://dx.doi.org/10.2174/1573396315666190118101953
Descripción
Sumario:Neonates represent a vulnerable population for infections and neonatal sepsis is a major cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most commonly pre-scribed drugs in the Neonatal Intensive Care Unit Setting but unfortunately are quite often used inap-propriately with various short and long-term effects. The rational use of antimicrobials is of para-mount importance in this population and structured antimicrobial stewardship interventions should be in place. These interventions are slightly different from those used in adults and older children due to the particularities of the neonatal medicine. The aim of this review is to provide an update in the field and identify areas for further consideration and future research