Structural basis for ligand recognition at the human MT(1) melatonin receptor

Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone that maintains circadian rhythm(1) by synchronization to environmental cues and is involved in diverse physiological processes(2) including blood pressure and core body temperature regulation, oncogenesis, and immune function(3). Formed in t...

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Detalles Bibliográficos
Autores principales: Stauch, Benjamin, Johansson, Linda C., McCorvy, John D., Patel, Nilkanth, Han, Gye Won, Huang, Xi-Ping, Gati, Cornelius, Batyuk, Alexander, Slocum, Samuel T., Ishchenko, Andrii, Brehm, Wolfgang, White, Thomas A., Michaelian, Nairie, Madsen, Caleb, Zhu, Lan, Grant, Thomas D., Grandner, Jessica M., Shiriaeva, Anna, Olsen, Reid H.J., Tribo, Alexandra R., Yous, Saïd, Stevens, Raymond C., Weierstall, Uwe, Katritch, Vsevolod, Roth, Bryan L., Liu, Wei, Cherezov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696938/
https://www.ncbi.nlm.nih.gov/pubmed/31019306
http://dx.doi.org/10.1038/s41586-019-1141-3

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