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A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice

Skeletal muscle cell (myofiber) atrophy is a detrimental component of aging and cancer that primarily results from muscle protein degradation via the proteasome and ubiquitin ligases. Transcriptional upregulation of some ubiquitin ligases contributes to myofiber atrophy, but little is known about th...

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Detalles Bibliográficos
Autores principales:	Hunt, Liam C., Stover, Jared, Haugen, Benard, Shaw, Timothy I., Li, Yuxin, Pagala, Vishwajeeth R., Finkelstein, David, Barton, Elisabeth R., Fan, Yiping, Labelle, Myriam, Peng, Junmin, Demontis, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697171/ https://www.ncbi.nlm.nih.gov/pubmed/31365869 http://dx.doi.org/10.1016/j.celrep.2019.06.094

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