Intercellular interaction dictates cancer cell ferroptosis via Merlin-YAP signalling

Ferroptosis, a cell death process driven by cellular metabolism and iron-dependent lipid peroxidation, is implicated in various diseases such as ischemic organ damage and cancer(1,2). As a central regulator of ferroptosis, the enzyme glutathione peroxidase 4 (GPX4) protects cells from ferroptosis by...

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Detalles Bibliográficos
Autores principales: Wu, Jiao, Minikes, Alexander M., Gao, Minghui, Bian, Huijie, Li, Yong, Stockwell, Brent R., Chen, Zhi-Nan, Jiang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697195/
https://www.ncbi.nlm.nih.gov/pubmed/31341276
http://dx.doi.org/10.1038/s41586-019-1426-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697195/
https://www.ncbi.nlm.nih.gov/pubmed/31341276
http://dx.doi.org/10.1038/s41586-019-1426-6

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