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Intercellular interaction dictates cancer cell ferroptosis via Merlin-YAP signalling
Ferroptosis, a cell death process driven by cellular metabolism and iron-dependent lipid peroxidation, is implicated in various diseases such as ischemic organ damage and cancer(1,2). As a central regulator of ferroptosis, the enzyme glutathione peroxidase 4 (GPX4) protects cells from ferroptosis by...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697195/ https://www.ncbi.nlm.nih.gov/pubmed/31341276 http://dx.doi.org/10.1038/s41586-019-1426-6 |