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Maternal choline supplementation ameliorates Alzheimer’s disease pathology by reducing brain homocysteine levels across multiple generations
The lack of effective treatments for Alzheimer’s disease (AD) is alarming considering the number of people currently affected by this disorder and the projected increase over the next few decades. Elevated homocysteine levels double the risk of developing AD. Choline, a primary dietary source of met...
Autores principales: | Velazquez, Ramon, Ferreira, Eric, Winslow, Wendy, Dave, Nikhil, Piras, Ignazio S., Naymik, Marcus, Huentelman, Matthew J, Tran, An, Caccamo, Antonella, Oddo, Salvatore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697226/ https://www.ncbi.nlm.nih.gov/pubmed/30622336 http://dx.doi.org/10.1038/s41380-018-0322-z |
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