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Batroxobin accelerated tissue repair via neutrophil extracellular trap regulation and defibrinogenation in a murine ischemic hindlimb model
Batroxobin, isolated from Bothrops moojeni, is a defibrinogenating agent used as a thrombin-like serine protease against fibrinogen for improving microcirculation. Here, we investigated whether, and if so, how batroxobin restores ischemic tissue injury in terms of anti-inflammatory effects. In an in...
Autores principales: | Masuda, Haruchika, Sato, Atsuko, Shizuno, Tomoko, Yokoyama, Keiko, Suzuki, Yusuke, Tokunaga, Masayoshi, Asahara, Takayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697371/ https://www.ncbi.nlm.nih.gov/pubmed/31419236 http://dx.doi.org/10.1371/journal.pone.0220898 |
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