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Interaction Between the a3 Region of Factor VIII and the TIL’E’ Domains of the von Willebrand Factor

The von Willebrand factor (VWF) and coagulation factor VIII (FVIII) are intricately involved in hemostasis. A tight, noncovalent complex between VWF and FVIII prolongs the half-life of FVIII in plasma, and failure to form this complex leads to rapid clearance of FVIII and bleeding diatheses such as...

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Detalles Bibliográficos
Autores principales:	Dagil, Lisbeth, Troelsen, Kathrin S., Bolt, Gert, Thim, Lars, Wu, Bo, Zhao, Xin, Tuddenham, Edward G.D., Nielsen, Thomas E., Tanner, David A., Faber, Johan H., Breinholt, Jens, Rasmussen, Jakob E., Hansen, D. Flemming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697466/ https://www.ncbi.nlm.nih.gov/pubmed/31349985 http://dx.doi.org/10.1016/j.bpj.2019.07.007

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