V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss

Phosphatase and tensin homolog (PTEN) tumor suppressor protein loss is common in prostate cancer (PCa). PTEN loss increases PI3K/Akt signaling, which promotes cell growth and survival. To find secreted biomarkers of PTEN loss, a proteomic screen was used to compare secretomes of cells with and witho...

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Detalles Bibliográficos
Autores principales: Mohammad, Amro H., Assadian, Sarah, Couture, Frédéric, Lefebvre, Karen J., El-Assaad, Wissal, Barrès, Veronique, Ouellet, Veronique, Boulay, Pierre-Luc, Yang, Jieyi, Latour, Mathieu, Furic, Luc, Muller, William, Sonenberg, Nahum, Mes-Masson, Anne-Marie, Saad, Fred, Day, Robert, Teodoro, Jose G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697641/
https://www.ncbi.nlm.nih.gov/pubmed/31452834
http://dx.doi.org/10.18632/oncotarget.27075

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