STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation

Efferocytosis of apoptotic neutrophils (PMNs) by alveolar macrophages (AMФs) is vital for resolution of inflammation and tissue injury. Here, we investigated the role of AMФ polarization and expression of the efferocytic ligand Gas6 in restoring homeostasis. In the murine model of lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Nepal, Saroj, Tiruppathi, Chinnaswamy, Tsukasaki, Yoshikazu, Farahany, Joseph, Mittal, Manish, Rehman, Jalees, Prockop, Darwin J., Malik, Asrar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697797/
https://www.ncbi.nlm.nih.gov/pubmed/31363052
http://dx.doi.org/10.1073/pnas.1821601116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697797/
https://www.ncbi.nlm.nih.gov/pubmed/31363052
http://dx.doi.org/10.1073/pnas.1821601116

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