Cargando…

Regulation of CCL2 expression in human vascular endothelial cells by a neighboring divergently transcribed long noncoding RNA

Atherosclerosis is a chronic inflammatory disease that is driven, in part, by activation of vascular endothelial cells (ECs). In response to inflammatory stimuli, the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway orchestrates the expression of a network of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khyzha, Nadiya, Khor, Melvin, DiStefano, Peter V., Wang, Liangxi, Matic, Ljubica, Hedin, Ulf, Wilson, Michael D., Maegdefessel, Lars, Fish, Jason E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697820/ https://www.ncbi.nlm.nih.gov/pubmed/31350345 http://dx.doi.org/10.1073/pnas.1904108116

Ejemplares similares

Kinship and familiarity mitigate costs of social conflict between Seychelles warbler neighbors
por: Bebbington, Kat, et al.
Publicado: (2017)

Changes in resource partitioning between and within organs support growth adjustment to neighbor proximity in Brassicaceae seedlings
por: de Wit, Mieke, et al.
Publicado: (2018)

Ancient polymorphisms and divergence hitchhiking contribute to genomic islands of divergence within a poplar species complex
por: Ma, Tao, et al.
Publicado: (2018)

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner
por: Mgrditchian, Takouhie, et al.
Publicado: (2017)

A major role for noncoding regulatory mutations in the evolution of enzyme activity
por: Loehlin, David W., et al.
Publicado: (2019)

Point centromere activity requires an optimal level of centromeric noncoding RNA
por: Ling, Yick Hin, et al.
Publicado: (2019)

Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella
por: Hammarlöf, Disa L., et al.
Publicado: (2018)

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes
por: Shurtleff, Matthew J., et al.
Publicado: (2017)

Divergent kinase regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole
por: Beraki, Tsebaot, et al.
Publicado: (2019)

Global analysis of ribosome-associated noncoding RNAs unveils new modes of translational regulation
por: Bazin, Jérémie, et al.
Publicado: (2017)

Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function
por: Raveendra, Bindu L., et al.
Publicado: (2018)

Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
por: Li, Dongqing, et al.
Publicado: (2019)

Divergent allocation of sperm and the seminal proteome along a competition gradient in Drosophila melanogaster
por: Hopkins, Ben R., et al.
Publicado: (2019)

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons
por: Briese, Michael, et al.
Publicado: (2018)

Divergence of regulatory networks governed by the orthologous transcription factors FLC and PEP1 in Brassicaceae species
por: Mateos, Julieta L., et al.
Publicado: (2017)

QTL × environment interactions underlie adaptive divergence in switchgrass across a large latitudinal gradient
por: Lowry, David B., et al.
Publicado: (2019)

Phytophthora palmivora establishes tissue-specific intracellular infection structures in the earliest divergent land plant lineage
por: Carella, Philip, et al.
Publicado: (2018)

Long noncoding RNA LINC00673-v4 promotes aggressiveness of lung adenocarcinoma via activating WNT/β-catenin signaling
por: Guan, Hongyu, et al.
Publicado: (2019)

Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library
por: Merkouris, Spyros, et al.
Publicado: (2018)

Childhood trauma history is linked to abnormal brain connectivity in major depression
por: Yu, Meichen, et al.
Publicado: (2019)

Gene cluster conservation provides insight into cercosporin biosynthesis and extends production to the genus Colletotrichum
por: de Jonge, Ronnie, et al.
Publicado: (2018)

Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy
por: Cartier, Andreane, et al.
Publicado: (2020)

Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase
por: Imberdis, Thibaut, et al.
Publicado: (2019)

Mechanism of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophils
por: Noack, Andreas, et al.
Publicado: (2018)

Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis
por: Chen, QiXing, et al.
Publicado: (2019)

High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
por: Sago, Cory D., et al.
Publicado: (2018)

Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice
por: Xie, Kan, et al.
Publicado: (2018)

Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics
por: Krause, Matthew D., et al.
Publicado: (2018)

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction
por: Hillig, Roman C., et al.
Publicado: (2019)

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation
por: Gehrmann, Ulf, et al.
Publicado: (2019)

Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor
por: Spurny, Radovan, et al.
Publicado: (2015)

Metabolic and trophic interactions modulate methane production by Arctic peat microbiota in response to warming
por: Tveit, Alexander Tøsdal, et al.
Publicado: (2015)

Regulation of age-related macular degeneration-like pathology by complement factor H
por: Toomey, Christopher B., et al.
Publicado: (2015)

Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
por: Babapoor-Farrokhran, Savalan, et al.
Publicado: (2015)

BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met
por: Mizui, Toshiyuki, et al.
Publicado: (2015)

Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy
por: Barrett, Christian L., et al.
Publicado: (2015)

Reduced endogenous Ca(2+) buffering speeds active zone Ca(2+) signaling
por: Delvendahl, Igor, et al.
Publicado: (2015)

Paclitaxel-induced epithelial damage and ectopic MMP-13 expression promotes neurotoxicity in zebrafish
por: Lisse, Thomas S., et al.
Publicado: (2016)

Analysis of high-resolution 3D intrachromosomal interactions aided by Bayesian network modeling
por: Zhang, Xizhe, et al.
Publicado: (2017)

Sparsity enables estimation of both subcortical and cortical activity from MEG and EEG
por: Krishnaswamy, Pavitra, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_l7m9ph68d4t86rhvlad5k6qd0b