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Expression and Evaluation of HuscFv Antibody -PE40 Immunotoxin for Target Therapy of EGFR-Overexpressing Cancers

BACKGROUND: Epidermal growth factor receptor (EGFR) plays an important role in the progression and tumorigenesis of the various cancers. In this regards, anti-EGFR antibodies are valuable approved therapeutics for the EGFR over-expressing cancers. However, the occurrence of mutations in the EGFR and...

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Detalles Bibliográficos
Autores principales: Falahatgar, Dianoush, Farajnia, Safar, Zarghami, Nosratollah, Tanomand, Asghar, Khosroshahi, Shiva Ahdi, Akbari, Bahman, Farajnia, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697836/
https://www.ncbi.nlm.nih.gov/pubmed/31457033
http://dx.doi.org/10.21859/ijb.1743