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Expression and Evaluation of HuscFv Antibody -PE40 Immunotoxin for Target Therapy of EGFR-Overexpressing Cancers
BACKGROUND: Epidermal growth factor receptor (EGFR) plays an important role in the progression and tumorigenesis of the various cancers. In this regards, anti-EGFR antibodies are valuable approved therapeutics for the EGFR over-expressing cancers. However, the occurrence of mutations in the EGFR and...
Autores principales: | Falahatgar, Dianoush, Farajnia, Safar, Zarghami, Nosratollah, Tanomand, Asghar, Khosroshahi, Shiva Ahdi, Akbari, Bahman, Farajnia, Hadi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Genetic Engineering and Biotechnology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697836/ https://www.ncbi.nlm.nih.gov/pubmed/31457033 http://dx.doi.org/10.21859/ijb.1743 |
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