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RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression

BACKGROUND: With the advent of array-based techniques to measure methylation levels in primary tumor samples, systematic investigations of methylomes have widely been performed on a large number of tumor entities. Most of these approaches are not based on measuring individual cell methylation but ra...

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Detalles Bibliográficos
Autores principales: Johann, Pascal David, Jäger, Natalie, Pfister, Stefan M., Sill, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697926/
https://www.ncbi.nlm.nih.gov/pubmed/31419933
http://dx.doi.org/10.1186/s12859-019-3014-z