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11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy

BACKGROUND: Despite their efficacy in the treatment of chronic inflammation, the prolonged application of therapeutic glucocorticoids (GCs) is limited by significant systemic side effects including glucocorticoid-induced osteoporosis (GIOP). 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a bi...

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Detalles Bibliográficos
Autores principales:	Fenton, C. G., Doig, C. L., Fareed, S., Naylor, A., Morrell, A. P., Addison, O., Wehmeyer, C., Buckley, C. D., Cooper, M. S., Lavery, G. G., Raza, K., Hardy, R. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698000/ https://www.ncbi.nlm.nih.gov/pubmed/31420008 http://dx.doi.org/10.1186/s13075-019-1972-1

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