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Correlation between Estrogen Levels with Lipid Profile in Menopause Women in West Sumatera

BACKGROUND: Menopause is a condition where women had not experienced menstruation for 12 consecutive cycles. At menopause period, there is alteration in women reproductive cycle where estrogen decreased and lipid status altered. AIM: This study is aimed to understand the association of estrogen leve...

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Detalles Bibliográficos
Autores principales: Ariadi, Ariadi, Jamsari, Jamsari, Yanwirasti, Yanwirasti, Siregar, Muhammad Fidel Ganis, Yusrawati, Yusrawati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698113/
https://www.ncbi.nlm.nih.gov/pubmed/31456830
http://dx.doi.org/10.3889/oamjms.2019.627
Descripción
Sumario:BACKGROUND: Menopause is a condition where women had not experienced menstruation for 12 consecutive cycles. At menopause period, there is alteration in women reproductive cycle where estrogen decreased and lipid status altered. AIM: This study is aimed to understand the association of estrogen level and lipid status in menopause women. METHODS: This study was an observational study with cross-sectional design underwent in Obstetrics and Gynecology Polyclinic Dr M. Djamil Hospital, Padang to examine estrogen level and lipid level in 107 menopause women aged between 40-60 years old. The study was conducted for 6 months. The relationship between estrogen level and lipid profile was done using correlation test and p-value < 0.05 is significant. RESULTS: There was no significant correlation between estrogen and total cholesterol (p = 0.146), LDL (p = 0.496), HDL (p = 0.172) and triglyceride (p = 0.296) in menopause women. There was negative correlation between estrogen with total cholesterol (r = -0.141; p = 0.146), HDL (r = -0.133; p = 0.172) and triglyceride (r = -0.1; p = 0.296) and a little positive correlation with LDL (r = 0.06; p = 0.496). Estrogen levels are not related to total Cholesterol, LDL, HDL, and triglyceride in menopause women CONCLUSION: Estrogen levels did not correlate with lipid status in menopause women in West Sumatera.