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Amino Acid Biosynthesis Regulation during Endoplasmic Reticulum Stress Is Coupled to Protein Expression Demands
The endoplasmic reticulum (ER) stress response, also known as the unfolded protein response (UPR), is a complex cellular response to ER protein misfolding that involves transcriptional regulatory branches and a PERK-mediated translational regulatory branch. Here we revealed that amino acid biosynthe...
Autores principales: | Gonen, Nir, Meller, Anatoly, Sabath, Niv, Shalgi, Reut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698312/ https://www.ncbi.nlm.nih.gov/pubmed/31377665 http://dx.doi.org/10.1016/j.isci.2019.07.022 |
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