Cargando…
Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology
Cortical iron has been shown to be elevated in Alzheimer’s disease (AD), but the impact of directly measured iron on the clinical syndrome has not been assessed. We investigated the association between post-mortem iron levels with the clinical and pathological diagnosis of AD, its severity, and the...
Autores principales: | Ayton, Scott, Wang, Yamin, Diouf, Ibrahima, Schneider, Julie A, Brockman, John, Morris, Martha Clare, Bush, Ashley I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698435/ https://www.ncbi.nlm.nih.gov/pubmed/30778133 http://dx.doi.org/10.1038/s41380-019-0375-7 |
Ejemplares similares
-
Cellular Senescence and Iron Dyshomeostasis in Alzheimer’s Disease
por: Masaldan, Shashank, et al.
Publicado: (2019) -
Age and cognitive decline in the UK Biobank
por: Cornelis, Marilyn C., et al.
Publicado: (2019) -
The essential elements of Alzheimer’s disease
por: Lei, Peng, et al.
Publicado: (2020) -
A delicate balance: Iron metabolism and diseases of the brain
por: Hare, Dominic, et al.
Publicado: (2013) -
Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE
por: Ayton, Scott, et al.
Publicado: (2015)