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Tumor Necrosis Factor-α Produced by Osteoclasts Might Induce Intractable Pain in a Rat Spinal Metastasis Model of Breast Cancer

INTRODUCTION: Causes of pain due to spinal metastases have been insufficiently investigated. Tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) were the focus of this study. Both are known as proinflammatory cytokines associated with the pathophysiology of pain syndromes(1)()). It is well know...

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Detalles Bibliográficos
Autores principales:	Mazaki, Ai, Orita, Sumihisa, Inage, Kazuhide, Suzuki, Miyako, Abe, Kohki, Shiga, Yasuhiro, Inoue, Masahiro, Norimoto, Masaki, Umimura, Tomotaka, Ohtori, Seiji, Yamauchi, Kazuyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society for Spine Surgery and Related Research 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698511/ https://www.ncbi.nlm.nih.gov/pubmed/31440686 http://dx.doi.org/10.22603/ssrr.2018-0106

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