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HIF1α/PD-L1 axis mediates hypoxia-induced cell apoptosis and tumor progression in follicular thyroid carcinoma

BACKGROUND: Hypoxia-inducible factor 1α (HIF-1α) and programmed cell death-1 protein ligand 1 (PD-L1) are implicated in the metastasis and progression processes of multiple cancers. Hypoxia selectively elevates PD-L1 expression via HIF1α activation in several solid tumors; however, the regulatory ef...

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Detalles Bibliográficos
Autores principales:	Zhou, Lingyan, Cha, Guofen, Chen, Liyu, Yang, Chen, Xu, Dong, Ge, Minghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698605/ https://www.ncbi.nlm.nih.gov/pubmed/31616157 http://dx.doi.org/10.2147/OTT.S203724

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