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hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles

Alternative cleavage and polyadenylation (APA) can occur at more than half of all human genes, greatly enhancing the cellular repertoire of mRNA isoforms. As these isoforms can have altered stability, localisation and coding potential, deregulation of APA can disrupt gene expression and this has bee...

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Detalles Bibliográficos
Autores principales:	Fischl, Harry, Neve, Jonathan, Wang, Zhiqiao, Patel, Radhika, Louey, Alastair, Tian, Bin, Furger, Andre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698646/ https://www.ncbi.nlm.nih.gov/pubmed/31147722 http://dx.doi.org/10.1093/nar/gkz461

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