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FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences
The growing prevalence of deadly microbes with resistance to previously life-saving drug therapies is a dire threat to human health. Detection of low abundance pathogen sequences remains a challenge for metagenomic Next Generation Sequencing (NGS). We introduce FLASH (Finding Low Abundance Sequences...
Autores principales: | Quan, Jenai, Langelier, Charles, Kuchta, Alison, Batson, Joshua, Teyssier, Noam, Lyden, Amy, Caldera, Saharai, McGeever, Aaron, Dimitrov, Boris, King, Ryan, Wilheim, Jordan, Murphy, Maxwell, Ares, Lara Pesce, Travisano, Katherine A, Sit, Rene, Amato, Roberto, Mumbengegwi, Davis R, Smith, Jennifer L, Bennett, Adam, Gosling, Roly, Mourani, Peter M, Calfee, Carolyn S, Neff, Norma F, Chow, Eric D, Kim, Peter S, Greenhouse, Bryan, DeRisi, Joseph L, Crawford, Emily D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698650/ https://www.ncbi.nlm.nih.gov/pubmed/31114866 http://dx.doi.org/10.1093/nar/gkz418 |
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