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A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling

Preblastoderm Drosophila embryo development is characterized by fast cycles of nuclear divisions. Extracts from these embryos can be used to reconstitute complex chromatin with high efficiency. We now discovered that this chromatin assembly system contains activities that recognize unprotected DNA e...

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Detalles Bibliográficos
Autores principales:	Harpprecht, Lisa, Baldi, Sandro, Schauer, Tamas, Schmidt, Andreas, Bange, Tanja, Robles, Maria S, Kremmer, Elisabeth, Imhof, Axel, Becker, Peter B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698661/ https://www.ncbi.nlm.nih.gov/pubmed/31147711 http://dx.doi.org/10.1093/nar/gkz473

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