MethylCal: Bayesian calibration of methylation levels

Bisulfite amplicon sequencing has become the primary choice for single-base methylation quantification of multiple targets in parallel. The main limitation of this technology is a preferential amplification of an allele and strand in the PCR due to methylation state. This effect, known as ‘PCR bias&...

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Detalles Bibliográficos
Autores principales: Ochoa, Eguzkine, Zuber, Verena, Fernandez-Jimenez, Nora, Bilbao, Jose Ramon, Clark, Graeme R, Maher, Eamonn R, Bottolo, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698668/
https://www.ncbi.nlm.nih.gov/pubmed/31049595
http://dx.doi.org/10.1093/nar/gkz325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698668/
https://www.ncbi.nlm.nih.gov/pubmed/31049595
http://dx.doi.org/10.1093/nar/gkz325

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