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Fetal hypoxia and hyperglycemia in the formation of phenytoin‐induced cleft lip and maxillary hypoplasia

OBJECTIVE: Phenytoin exposure during the first trimester of pregnancy increases the risk of maxillary hypoplasia and cleft lip. The etiology of phenytoin embryopathy is unknown. Interestingly, phenytoin is also known to induce hyperglycemia in humans as well as rats. This study uses a rat model of f...

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Detalles Bibliográficos
Autores principales:	Ritchie, Helen E., Oakes, Diana, Farrell, Emma, Ababneh, Deena, Howe, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Full‐length Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698684/ https://www.ncbi.nlm.nih.gov/pubmed/31440725 http://dx.doi.org/10.1002/epi4.12352

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