Toxin–antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA–KacT complex

Bacterial toxin–antitoxin pairs play important roles in bacterial multidrug tolerance. Gcn5-related N-acetyltransferase (GNAT) toxins inhibit translation by acetylation of aminoacyl-tRNAs and are counteracted by direct contacts with cognate ribbon–helix–helix (RHH) antitoxins. Our previous analysis...

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Detalles Bibliográficos
Autores principales: Qian, Hongliang, Yu, Hao, Li, Peifei, Zhu, E, Yao, Qingqing, Tai, Cui, Deng, Zixin, Gerdes, Kenn, He, Xinyi, Gan, Jianhua, Ou, Hong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698736/
https://www.ncbi.nlm.nih.gov/pubmed/31260525
http://dx.doi.org/10.1093/nar/gkz563

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