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Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon
The purpose of this study is to investigate the dosimetric impact of multi‐leaf collimator (MLC) positioning errors on a Varian Halcyon for both random and systematic errors, and to evaluate the effectiveness of portal dosimetry quality assurance in catching clinically significant changes caused by...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698762/ https://www.ncbi.nlm.nih.gov/pubmed/31294923 http://dx.doi.org/10.1002/acm2.12677 |
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author | Gay, Skylar S. Netherton, Tucker J. Cardenas, Carlos E. Ger, Rachel B. Balter, Peter A. Dong, Lei Mihailidis, Dimitris Court, Laurence E. |
author_facet | Gay, Skylar S. Netherton, Tucker J. Cardenas, Carlos E. Ger, Rachel B. Balter, Peter A. Dong, Lei Mihailidis, Dimitris Court, Laurence E. |
author_sort | Gay, Skylar S. |
collection | PubMed |
description | The purpose of this study is to investigate the dosimetric impact of multi‐leaf collimator (MLC) positioning errors on a Varian Halcyon for both random and systematic errors, and to evaluate the effectiveness of portal dosimetry quality assurance in catching clinically significant changes caused by these errors. Both random and systematic errors were purposely added to 11 physician‐approved head and neck volumetric modulated arc therapy (VMAT) treatment plans, yielding a total of 99 unique plans. Plans were then delivered on a preclinical Varian Halcyon linear accelerator and the fluence was captured by an opposed portal dosimeter. When comparing dose–volume histogram (DVH) values of plans with introduced MLC errors to known good plans, clinically significant changes to target structures quickly emerged for plans with systematic errors, while random errors caused less change. For both error types, the magnitude of clinically significant changes increased as error size increased. Portal dosimetry was able to detect all systematic errors, while random errors of ±5 mm or less were unlikely to be detected. Best detection of clinically significant errors, while minimizing false positives, was achieved by following the recommendations of AAPM TG‐218. Furthermore, high‐ to moderate correlation was found between dose DVH metrics for normal tissues surrounding the target and portal dosimetry pass rates. Therefore, it may be concluded that portal dosimetry on the Halcyon is robust enough to detect errors in MLC positioning before they introduce clinically significant changes to VMAT treatment plans. |
format | Online Article Text |
id | pubmed-6698762 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-66987622019-08-22 Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon Gay, Skylar S. Netherton, Tucker J. Cardenas, Carlos E. Ger, Rachel B. Balter, Peter A. Dong, Lei Mihailidis, Dimitris Court, Laurence E. J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study is to investigate the dosimetric impact of multi‐leaf collimator (MLC) positioning errors on a Varian Halcyon for both random and systematic errors, and to evaluate the effectiveness of portal dosimetry quality assurance in catching clinically significant changes caused by these errors. Both random and systematic errors were purposely added to 11 physician‐approved head and neck volumetric modulated arc therapy (VMAT) treatment plans, yielding a total of 99 unique plans. Plans were then delivered on a preclinical Varian Halcyon linear accelerator and the fluence was captured by an opposed portal dosimeter. When comparing dose–volume histogram (DVH) values of plans with introduced MLC errors to known good plans, clinically significant changes to target structures quickly emerged for plans with systematic errors, while random errors caused less change. For both error types, the magnitude of clinically significant changes increased as error size increased. Portal dosimetry was able to detect all systematic errors, while random errors of ±5 mm or less were unlikely to be detected. Best detection of clinically significant errors, while minimizing false positives, was achieved by following the recommendations of AAPM TG‐218. Furthermore, high‐ to moderate correlation was found between dose DVH metrics for normal tissues surrounding the target and portal dosimetry pass rates. Therefore, it may be concluded that portal dosimetry on the Halcyon is robust enough to detect errors in MLC positioning before they introduce clinically significant changes to VMAT treatment plans. John Wiley and Sons Inc. 2019-07-11 /pmc/articles/PMC6698762/ /pubmed/31294923 http://dx.doi.org/10.1002/acm2.12677 Text en © 2019 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Gay, Skylar S. Netherton, Tucker J. Cardenas, Carlos E. Ger, Rachel B. Balter, Peter A. Dong, Lei Mihailidis, Dimitris Court, Laurence E. Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon |
title | Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon |
title_full | Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon |
title_fullStr | Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon |
title_full_unstemmed | Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon |
title_short | Dosimetric impact and detectability of multi‐leaf collimator positioning errors on Varian Halcyon |
title_sort | dosimetric impact and detectability of multi‐leaf collimator positioning errors on varian halcyon |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698762/ https://www.ncbi.nlm.nih.gov/pubmed/31294923 http://dx.doi.org/10.1002/acm2.12677 |
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