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The Pyrin Inflammasome in Health and Disease

The pyrin inflammasome has evolved as an innate immune sensor to detect bacterial toxin-induced Rho guanosine triphosphatase (Rho GTPase)-inactivation, a process that is similar to the “guard” mechanism in plants. Rho GTPases act as molecular switches to regulate a variety of signal transduction pat...

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Detalles Bibliográficos
Autores principales: Schnappauf, Oskar, Chae, Jae Jin, Kastner, Daniel L., Aksentijevich, Ivona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698799/
https://www.ncbi.nlm.nih.gov/pubmed/31456795
http://dx.doi.org/10.3389/fimmu.2019.01745

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