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Process Analytical Approach towards Quality Controlled Process Automation for the Downstream of Protein Mixtures by Inline Concentration Measurements Based on Ultraviolet/Visible Light (UV/VIS) Spectral Analysis

Downstream of pharmaceutical proteins, such as monoclonal antibodies, is mainly done by chromatography, where concentration determination of coeluting components presents a major problem. Inline concentration measurements (ICM) by Ultraviolet/Visible light (UV/VIS)-spectral data analysis provide a l...

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Detalles Bibliográficos
Autores principales:	Zobel-Roos, Steffen, Mouellef, Mourad, Siemers, Christian, Strube, Jochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698811/ https://www.ncbi.nlm.nih.gov/pubmed/31548539 http://dx.doi.org/10.3390/antib6040024

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