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Small-Format Drug Conjugates: A Viable Alternative to ADCs for Solid Tumours?
Antibody–Drug Conjugates (ADCs) have been through multiple cycles of technological innovation since the concept was first practically demonstrated ~40 years ago. Current technology is focusing on large, whole immunoglobulin formats (of which there are approaching 100 in clinical development), many w...
Autores principales: | Deonarain, Mahendra P., Yahioglu, Gokhan, Stamati, Ioanna, Pomowski, Anja, Clarke, James, Edwards, Bryan M., Diez-Posada, Soraya, Stewart, Ashleigh C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698822/ https://www.ncbi.nlm.nih.gov/pubmed/31544868 http://dx.doi.org/10.3390/antib7020016 |
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