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Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders
The effector functions of T lymphocytes are responsible for most autoimmune disorders and act by directly damaging tissues or by indirectly promoting inflammation and antibody responses. Co-stimulatory and co-inhibitory T cell receptor molecules are the primary pharmacological targets that enable in...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698823/ https://www.ncbi.nlm.nih.gov/pubmed/31548534 http://dx.doi.org/10.3390/antib6040019 |