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Infusion Reactions Associated with the Medical Application of Monoclonal Antibodies: The Role of Complement Activation and Possibility of Inhibition by Factor H

Human application of monoclonal antibodies (mAbs), enzymes, as well as contrast media and many other particulate drugs and agents referred to as “nanomedicines”, can initiate pseudoallergic hypersensitivity reactions, also known as infusion reactions. These may in part be mediated by the activation...

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Detalles Bibliográficos
Autores principales: Fülöp, Tamás, Mészáros, Tamás, Kozma, Gergely Tibor, Szebeni, János, Józsi, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698840/
https://www.ncbi.nlm.nih.gov/pubmed/31544866
http://dx.doi.org/10.3390/antib7010014