Resveratrol reduces store-operated Ca(2+) entry and enhances the apoptosis of fibroblast-like synoviocytes in adjuvant arthritis rats model via targeting ORAI1–STIM1 complex

BACKGROUND: Resveratrol was reported to trigger the apoptosis of fibroblast-like synoviocytes in adjuvant arthritis rats but the subcellular mechanism remains unclear. Since ER stress, mitochondrial dysfunction and oxidative stress were involved in the effects of resveratrol with imbalance of calciu...

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Detalles Bibliográficos
Autores principales: Lu, Jinsen, Yang, Jiazhao, Zheng, Yongshun, Fang, Shiyuan, Chen, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699118/
https://www.ncbi.nlm.nih.gov/pubmed/31426853
http://dx.doi.org/10.1186/s40659-019-0250-7

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