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Peglated-H1/pHGFK1 nanoparticles enhance anti-tumor effects of sorafenib by inhibition of drug-induced autophagy and stemness in renal cell carcinoma

BACKGROUND: Tumor targeting small molecular inhibitors are the most popular treatments for many malignant diseases, including cancer. However, the lower clinical response and drug resistance still limit their clinical efficacies. HGFK1, the first kringle domain of hepatocyte growth factor, has been...

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Detalles Bibliográficos
Autores principales:	Gao, Xiaoge, Jiang, Pin, Zhang, Qian, Liu, Qian, Jiang, Shuangshuang, Liu, Ling, Guo, Maomao, Cheng, Qian, Zheng, Junnian, Yao, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699135/ https://www.ncbi.nlm.nih.gov/pubmed/31426831 http://dx.doi.org/10.1186/s13046-019-1348-z

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