Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report

Primary spinal epidural diffuse large B-cell lymphoma (DLBCL) is rare and often easily misdiagnose. Here, we presented a case of primary spinal epidural DLBCL with paraplegia as the first manifestation. He was misdiagnosed as thoracic disc herniation and thoracic tuberculosis successively. DLBCL was...

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Autores principales: Shu, Yefei, Wang, Anlong, Yi, Li, Xu, Xiaofeng, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699147/
https://www.ncbi.nlm.nih.gov/pubmed/31616159
http://dx.doi.org/10.2147/OTT.S217703
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author Shu, Yefei
Wang, Anlong
Yi, Li
Xu, Xiaofeng
Yang, Wei
author_facet Shu, Yefei
Wang, Anlong
Yi, Li
Xu, Xiaofeng
Yang, Wei
author_sort Shu, Yefei
collection PubMed
description Primary spinal epidural diffuse large B-cell lymphoma (DLBCL) is rare and often easily misdiagnose. Here, we presented a case of primary spinal epidural DLBCL with paraplegia as the first manifestation. He was misdiagnosed as thoracic disc herniation and thoracic tuberculosis successively. DLBCL was confirmed after surgery ultimately. After 6 cycles of chemotherapy with R-CHOPE, the patient went back to normal life without relapse during 2-year follow-up. Primary spinal epidural lymphoma should be suspected in patients with spinal cord compression with imaging showing isointense, homogeneous extradural contiguous level compressive soft‑tissue lesion without bony involvement and previous history of cancer.
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spelling pubmed-66991472019-10-15 Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report Shu, Yefei Wang, Anlong Yi, Li Xu, Xiaofeng Yang, Wei Onco Targets Ther Case Report Primary spinal epidural diffuse large B-cell lymphoma (DLBCL) is rare and often easily misdiagnose. Here, we presented a case of primary spinal epidural DLBCL with paraplegia as the first manifestation. He was misdiagnosed as thoracic disc herniation and thoracic tuberculosis successively. DLBCL was confirmed after surgery ultimately. After 6 cycles of chemotherapy with R-CHOPE, the patient went back to normal life without relapse during 2-year follow-up. Primary spinal epidural lymphoma should be suspected in patients with spinal cord compression with imaging showing isointense, homogeneous extradural contiguous level compressive soft‑tissue lesion without bony involvement and previous history of cancer. Dove 2019-08-14 /pmc/articles/PMC6699147/ /pubmed/31616159 http://dx.doi.org/10.2147/OTT.S217703 Text en © 2019 Shu et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Shu, Yefei
Wang, Anlong
Yi, Li
Xu, Xiaofeng
Yang, Wei
Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report
title Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report
title_full Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report
title_fullStr Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report
title_full_unstemmed Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report
title_short Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report
title_sort primary spinal epidural diffuse large b-cell lymphoma with paraplegia as the first manifestation: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699147/
https://www.ncbi.nlm.nih.gov/pubmed/31616159
http://dx.doi.org/10.2147/OTT.S217703
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